Journal: Biomedicines
Article Title: The Effects of Acute and Chronic Alcohol Administration and Withdrawal on Bone Microstructure, Mechanical Strength, and Remodeling Protein Expression and Their Relation to an Antioxidant and FGF23 In Vivo
doi: 10.3390/biomedicines12071515
Figure Lengend Snippet: The effects of alcohol administration and withdrawal on bone remodeling markers, an antioxidant, and FGF23. Abbreviations: NC: normal control group; AA: acute alcohol group; CA: chronic alcohol group; AW: alcohol withdrawal group. OCN: osteocalcin, OPN: osteopontin, RANKL: receptor activator of nuclear factor kappa-Β ligand, TRAP: tartrate-resistant acid phosphatase, FGF23: fibroblast growth factor 23, GPx: glutathione peroxidase. * p < 0.05, ** p < 0.01, *** p < 0.001, and **** p < 0.0001 indicate significant differences. The statistical test was performed using GraphPad Prism 10. The results are presented as the fold increase of the mean and standard error of the mean for 6 replicates and were normalized to the normal control in the respective group (fold increase = treatment group/normal control).
Article Snippet: Rat fibroblast growth factor 23 (FGF23) protein expression was measured using the Rat FGF23 ELISA Kit (Elabscience, E-EL-R2410), Rat tartrate-resistant acid phosphatase (TRAP) ACP5 protein expression was measured using the Rat TRAP ACP5 ELISA Kit (Elabscience, E-EL-R0939), and rat glutathione peroxidase (GPx) protein expression was measured using the Rat GPx ELISA Kit (Elabscience, E-EL-R2491).
Techniques: Control